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In our lab, we’re not just observing the AI revolution—we’re living it. We’re actively integrating AI, especially Large Language Models (LLMs), to fundamentally change how we do science. This isn’t about replacing your expertise; it’s about giving you superpowers to be more efficient, insightful, and impactful in your research, all while upholding the highest standards
All photos are 3D pictures, it was fun to try out the technology. Regrettably, the MRC defunded the MRC Cancer Unit and the School of Clinical Medicine could no longer support our Department. In the current academic job market, I am experiencing some uncertainties about where I will relocate. This is thus one of my
In fluorescence microscopy, colocalization is the spatial correlation between two different fluorescent labels. Often, we tag two proteins in a cell with distinct fluorescent labels, and we look if and where the staining localizes. When there is a “significant overlap” between the two signals we say that the two molecules “colocalize” and we might use
Industry, academia and healthcare often rely on fluorescence microscopy to see the fine architecture of materials, including biological ones. Fluorescence microscopy is particularly suited for biomedical studies because it can be gentle with biological materials permitting investigators to study biology in a non-destructive manner. Chemistry and genetic engineering then provide useful strategies to make samples
I am personally conflicted on this topic. I have recently started to work on machine learning and deep-learning specifically. Therefore, I am keen to explore the usefulness of these technologies, and I hope they will remove bottlenecks from our assays. My knowledge about CNNs is rather limited, even more so for SR and denoising applications.
Since a few months, the manuscript entitled “Multiplexed biochemical imaging reveals caspase activation patterns underlying single cell fate“, and authored by Maximilian W Fries, Kalina T Haas, Suzan Ber, John Saganty, Emma K Richardson, Ashok R Venkitaraman, Alessandro Esposito, is available as pre-print at the bioRxiv repository. It has started its journey through the peer-review process,
Well, I remember when I started this business, a beam stop was done with a recycled block of lead and reflections stopped with carton boxes 😉 Brown boxes, black carton catches fires, of course (tell this to my undergrad-self). Not any longer, of course! About ten years ago, I started the procurement and development of