Signalling and heterogeneity in biological systems and cancer
We combine live-cell imaging, biophotonics, systems biology, and mathematical modelling to understand how cells make decisions and how failures in these decisions can lead to cancer and disease.
Studying how KRAS mutations alter cell metabolism. (Dr Annie Howitt)
Research Themes
Cancer Biology
How signalling networks, oncogenic mutations, and heterogeneity shape cancer initiation and progression.
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Live scBiochemistry & biophotonics
Quantitative live-cell imaging, single-cell biochemistry, and advanced microscopy for biological discovery.
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Space Biology
Cell signalling and systems biology in microgravity and simulated space environments.
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We study how cells make decisions in cancer, imaging, and space biology, bringing together microscopy, biochemistry, modelling, and computation.
- Alessandro EspositoPrincipal Investigator
Resources, culture, outreach, and opportunities
Open science, research integrity, EDI, outreach, glossary, and archive material.